Additive manufacturing and technical strategies for improving outcomes in breast reconstructive surgery

Authors

  • Nicola Rocco G.RE.T.A. Group for Reconstructive and Therapeutic Advancements
  • Ida Papallo University of Naples Federico II
  • Maurizio Bruno Nava G.RE.T.A. Group for Reconstructive and Therapeutic Advancements
  • Giuseppe Catanuto G.RE.T.A. Group for Reconstructive and Therapeutic Advancements
  • Antonello Accurso Breast Unit, University Hospital Federico II,
  • Ilaria Onofrio Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II,
  • Olimpia Oliviero Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II,
  • Giovanni Improta Department of Public Health, University of Naples Federico II
  • Domenico Speranza Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio
  • Marco Domingos Department of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering, The University of Manchester
  • Teresa Russo Institute of Polymers, Composites and Biomaterials – National Research Council of Italy
  • Roberto De Santis Institute of Polymers, Composites and Biomaterials – National Research Council of Italy
  • Massimo Martorelli Department of Industrial Engineering, Fraunhofer JL IDEAS, University of Naples Federico II
  • Antonio Gloria Institute of Polymers, Composites and Biomaterials – National Research Council of Italy

DOI:

https://doi.org/10.21014/acta_imeko.v9i4.754

Abstract

It has been widely reported that breast reconstruction improves the quality of life of women who undergo mastectomy for breast cancer.
This approach provides many psychological advantages. Today, different techniques are available for the breast oncoplastic surgeon
that involve the use of breast implants and autologous tissues, also offering interesting results in terms of aesthetic and patient-reported
outcomes. On the other hand, advanced technologies and design strategies (i.e. design for additive manufacturing, reverse engineering)
may allow the development of customised porous structures with tailored morphological, mechanical, biological, and mass transport
properties. For this reason, the current study deals with the challenges, principles, and methods of developing 3D additive manufactured
structures in breast reconstructive surgery. Specifically, the aim was to design 3D additive manufactured poly(ε-caprolactone) scaffolds
with different architectures (i.e. lay-down patterns). Preliminary mechanical and biological analyses have shown the effect of the lay-
down pattern on the performances of the manufactured structures.

Author Biography

Ida Papallo, University of Naples Federico II

Department of Advanced Biomedical Sciences

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Published

2020-12-17

Issue

Section

Research Papers