Pulse transit time estimation methods in a novel arterial simulator with variable pulse wave velocity

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DOI:

https://doi.org/10.21014/actaimeko.v13i4.1782

Keywords:

Pulse wave velocity, pulse transit time, arterial simulator, arterial stiffness, cross-correlation

Abstract

Arterial stiffness is one of the key indicators of cardiovascular diseases, for which an early identification is crucial. Pulse Wave Velocity (PWV) is a widely used parameter to assess arterial stiffness. In clinical practice, it is common use to measure the PWV through the estimation of the Pulse Transit Time (PTT). In this study a comparison among three PTT estimation methods (peak-to-peak, tangent-secant, and cross-correlation) is proposed and applied to waveforms acquired on a novel arterial simulator able to change the stiffness of an arterial surrogate by varying the transmural pressure. After a measurement campaign carried out for several pressure values, the cross-correlation method has been confirmed to be the most robust, with uncertainties below 1.3 %. The operating principle of the arterial simulator has been confirmed since a change in transmural pressure of 25 kPa resulted in a change in PWV mean values of up to 1.7 m/s.

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Published

2024-11-22

Issue

Vol. 13 No. 4 (2024)

Section

Research Papers

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Copyright (c) 2024 Federico Filippi, Giorgia Fiori, Gabriele Bocchetta, Vincenzo La Battaglia, Stefano Marini, Salvatore Andrea Sciuto, Andrea Scorza

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